The
Science Earth
Home » » Anemia in pregnancy

Anemia in pregnancy

Written By Admin on Thursday, May 26, 2016 | 10:29:00 PM

Anemia in pregnancy 


Normal hematological events associated with pregnancy .
- During pregnancy there is a 36% increase in the blood volume , the maximum is reached at 34 weeks gestation .
- The plasma volume increases 47-50 % and RBSs mass Increases only 17 % and reaches its maximum at term .
- There is relative hemodilution throughout pregnancy , and this reaches its maximum at 28 – 34 weeks .
This dilution effect lowers the Hb , HCT , and RBCs count , its causes no change in the MCV or  MCH .


Definition : 

- Hb value below the lower limits of normal not explained by the state of hydration .
Anemia during pregnancy 11 or 10.5 g/dl -
- Anemia is defined as reduction in the total circulating red blood cells . 
- 20 – 60 % of prenatal patients will be found to be anemic at sometimes during pregnancy . 
Causes of anemia during pregnancy : 

1- Acquired :

- Iron deficiency anemia . 
- Anemia caused by acute blood loss . 
- Anemia of inflammation or malignancy .
- Megaloplastic anemia .
- Acquired hemolytic anemia . 
- Aplastic or hypoplastic anemia .

2- Hereditary:


Thalassemia .-
Sickle cell hemoglobinopathies . -
Other hemoglobinopathies . -
. hemolytic anemia Hereditary-
Red blood cell disorders during pregnancy : 

1- Decreased erythrocyte production .

- Iron deficiency .
- Thalassemia . 
- Chronic disease . 
- Bone marrow failure . 
- Inflammation process . 
- Malignancy . 
- Folate deficiency . 
- Vit b12 deficiency .

2- Increase erythrocyte loss :

- Hemolytic anemia . 
- Chemical toxicity . 
- Hemoglobinopathies . 
- Clinical presentation .

Symptoms caused by anemia are those resulting from :

1 - tissue hypoxia : fatigue , weakness , pallor and exertional dyspnea .
2 cardiovascular system attempts to compensate for the anemia : palpitation and tachycardia .

3 - an underlying disease :

- Chronic infection .
- Chronic renal disease .
- Chronic liver disease .
- Multiple pregnancy .

Severe anemia is associated with :
- Congestive heart failure . 
- Multi organ failure . 
- Tissue hypoxia .
(source)
SHARE